Amyloidosis is a group of diseases characterized by the extracellular deposition of amorphous material with a fibrillar structure. Renal involvement represents the most common systemic manifestation in amyloidosis. The widely accepted classification categorizes amyloidosis based on the type of fibril-forming protein including Serum Amyloid A (AA), Immunoglobulin light chain (AL), and transthyretin (ATTR) amyloidosis. Heavy chain amyloidosis (AH) is a rare entity characterized by amyloid fibrils derived exclusively from fragments of the Ig heavy chain.
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Silvariño et al. (2024) studied this question.
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