Post-transplant proteinuria is a biomarker of renal injury with a multifactorial etiology, negatively affecting graft function and survival. Renal allograft damage manifesting as proteinuria may involve aldosterone, and its blockade can potentially benefit kidney transplant recipients. This study aimed to evaluate the effect of spironolactone treatment on proteinuria and graft function in kidney transplant recipients.
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Freitas et al. (2024) studied this question.
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