Adhesion of muscle stem cells to their niche provides stable anchorage, and biochemical and biomechanical signals required for quiescence. In their work, Robert Krauss and colleagues reveal the role of catenin/cadherin-based adhesion interactions in maintaining niche localization. To find out more about their work, we spoke to the first author, Margaret Hung, and the corresponding author, Robert Krauss, Professor in Cell, Developmental and Regenerative Biology at the Icahn School of Medicine, Mount Sinai.
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Hung et al. (2024) studied this question.
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