Comorbidities of autoimmune bullous dermatoses in North-Eastern Romania

AUTOIMMUNE BULLOUS DERMATOSES IN NORTH-EASTERN ROMANIA (Abstract): Autoimmune bullous dermatoses (ABDs) are associated with a variety of systemic comorbidities, determined either by skin pathology or by the e ffects of systemic corticosteroid treatment.The most important comorbidities encountered in autoimmune bullous dermatoses belong to the cardiovascular, neurological, psychiatric, me tabolic or infectious sphere.Materials and methods: We performed a retrospective observational study used the Minimum Basic Data Set of hospital discharges to review records of patients admitted to Sf Spiridon Iasi public hospital between 2015 and 2019 with a diagnosis of any autoimmune bullous disorder.The objectives were to describe the triggering factors and the comorbidity profile of patients with autoimmune bullous dermatoses.Results: The study included 225 patients, the most common autoimmune bullous dermatosis being pe mphigus vulgaris.Some comorbidities, diabetes mellitus, or high blood pressure are more o ften found in patients with bullous pemphigoid, while vulgar pemphigus is more commonly associated with other diseases of autoimmune etiology (autoimmune thyroiditis, vitiligo).Conclusions: Evaluation of triggering factors and comorbidities before starting treatment may assist in controlling the disease more swiftly and reducing the side effects of treatment in the management of ABDs.