Endobronchial coil lung volume reduction performed on patients with emphysema dominant COPD: Long term follow-up results

Endobronchial coil lung volume reduction performed on patients with emphysema dominant COPD: Long term follow-up resultsIntroduction: Chronic obstructive pulmonary disease (COPD) is a commonly seen, preventable, and treatable disease with permanent respiratory symptoms and air entrapment that is caused by particle exposure.In case of limited response to traditional treatment protocols, lung volume reduction may be performed in patients with emphysema dominant patterns.In this study, long term follow-up results of the patients who had been operated on by minimal invasive bronchoscopic lung volume reduction surgery by coil placement were reported. Materials and Methods:Records of the patients operated on by coil placement were retrospectively investigated, and pulmonary function test (PFT), echocardiography (ECHO), six-minute walking test (6MWT), tomography images, ventilation scintigraphy, and clinical summaries were evaluated.Out of 34 initial candidates, 18 patients were included in the study.Wilcoxon signed-rank test and Spearman's rho were utilized to compare interventions and follow-up testing. Results:The average age of 18 patients was 62 (50-74) years, and except for one patient, all were males (n= 17).Fifteen patients were operated bilaterally, and the rest were unilaterally operated, with an average of 10 coils placed per coil placement.An average of 90 days was between bronchoscopic coil placement, with a follow-up duration of 45 days in between.Mean total follow-up duration was 794 (± 424) days.Pneumonia and pneumonitis were seen in 33% of patients within the first month.Mortality from respiratory causes was found to be 11%, while mortality from all causes was found to be 22%.Statistical difference was observed regarding 6MWT after bronchoscopic volume reduction when compared the initial preoperative values.However, this difference was later lost statistically at the second follow-up performed after the completion of both sides.A benefit in improved resting saturation was observed after the second procedure, which was not evident after unilateral