Exploring the Efficacy of Neuroplasticity-Driven Speech Therapy for Post-Stroke Aphasia Recovery: A Multimodal Intervention Approach

Objective: This study investigated the efficacy of a multimodal speech therapy intervention informed by neuroplasticity principles in promoting post-stroke aphasia recovery. Methods: A quasi-experimental design with 17 participants, using pre- and post-test assessments to compare the intervention –incorporating Constraint-Induced Aphasia Therapy (CIAT), Melodic Intonation Therapy (MIT), Script Training, and Cognitive-Communication Therapy (CCT)– to traditional speech therapy in individuals with aphasia. The Boston Diagnostic Aphasia Examination (BDAE) and Mini-Mental State Examination (MMSE) assessed language and cognitive function, while the Functional Outcome Questionnaire for Aphasia (FOQ-A) and in-depth interviews evaluated functional communication and subjective experiences. Results: The intervention group demonstrated significant improvements in expressive language (25% increase vs. 12% control), receptive language (20% vs. 14% control), language comprehension (18% vs. 8% control), and cognitive performance (15% vs. 9% control). Qualitative findings revealed enhanced communicative effectiveness, increased confidence in verbal interactions, and improved quality of life in the intervention group. Conclusions: This multimodal, neuroplasticity-driven intervention improved language and cognitive function in individuals with post-stroke aphasia, demonstrating its potential as an effective rehabilitation strategy. Future research should focus on long-term efficacy, individual response variability, and intervention optimization.