The Role of Anti-Caries Agent Sodium Fluoride Application in Rampant Caries Patients

Background: Rampant caries poses a significant challenge in dental practice, particularly in patients with compromised oral health. Sodium fluoride (NaF) has long been recognized for its caries-preventive properties due to its ability to enhance remineralization and inhibit demineralization of dental enamel. However, its specific role in managing rampant caries remains a subject of investigation. Materials and Methods: A randomized controlled trial involving 50 patients diagnosed with rampant caries was conducted. The patients were divided into two groups: Group A received topical applications of NaF and group B received standard oral care without NaF application. The NaF group received biweekly applications of 2.26% NaF gel for a period of six months. Clinical evaluations and radiographic assessments were conducted at baseline and after the intervention period. Results: Following the six-month intervention, patients in group A demonstrated a significant reduction in caries progression compared to group B. The mean number of new carious lesions was 3.2 ± 1.5 in group A, whereas it was 6.8 ± 2.3 in group B (p < 0.001). Additionally, radiographic analysis revealed a higher rate of remineralization in group A, with a mean increase in mineral density of 15.4 ± 3.8% compared to 5.6 ± 2.1% in group B (p < 0.05). Conclusion: Topical application of NaF demonstrated efficacy in managing rampant caries by reducing caries progression and promoting remineralization of dental enamel. Incorporating NaF into the treatment regimen for patients with rampant caries can serve as an effective preventive measure to mitigate the disease burden and improve oral health outcomes.