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March 22, 2024Cancer Research0 citations

Abstract 2717: Bifunctional fusion protein PDL1sFv/MICAe for cancer immunotherapy

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JLJunyi LiYWYanzhang Wei

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Li et al. (2024) studied this question.

synapsesocial.com/papers/68e72f48b6db6435876a8632https://doi.org/10.1158/1538-7445.am2024-2717
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 2473: A novel anti-PD-1 and proIL-2 bifunctional fusion protein delivers potent anti-tumor activity via PD-1 checkpoint inhibition and tumor selective IL-2R agonism preferentially on antigen specific T cells2024
  2. 2Abstract 4341: A novel αPD-1/αVEGF/IL-21v tri-specific fusion protein exhibits potent antitumor efficacy beyond αPD-1/αVEGF bispecific therapy2026
  3. 3Abstract 2361: A PD1-antibody-attenuated IL-2 fusion protein activates immune cells leading to the inhibition of tumor growth in ex vivo human 3D tumor models2024 · 1 citations
  4. 4Abstract 4057: Beyond IL-2: The promise of anti PD-1-attenuated IL-2 fusion protein in cancer immunotherapy2024
  5. 5Abstract 4344: Interferon-α and PD-1 blockade mutually mask each other in a tumor-activated manner2026