Anatomical predictors of the clinical and morphological characteristics of central serous chorioretinopathy

Purpose. To study the relationship between axial length (AL) and morphological and clinical characteristics in acute central serous chorioretinopathy Methods. All patients received optical coherence tomography, fluorescein angiography (FA), optical biometry, and retro-mode scanning laser ophthalmoscopy. The distance between the leakage point and the center of the fovea was defined using FA images, and its correlation with AL, subfoveal choroidal thickness (SCT), central retinal thickness (CRT), and neurosensory detachment (NSD) area was calculated. A number of leaks, rate of bilateral involvement, and recurrence rate were evaluated. Results. Forty-seven patients (47 eyes) were included in this study (38 males, 9 females, mean age 43.5 ± 10.8 years). The distance between the leakage point and the center of the fovea had a correlation with AL (r = –0.38, p = 0.008), SCT (r = 0.51, p = 0.0004), and the area of NSD (r = 0.5, p = 0.0006) but not with CRT (r = –0.11, p = 0.45). A statistically significant difference in the distance between the leakage point and the center of the fovea was found between eyes with short (23.0 mm), medium (23.0–24.0 mm), and long (> 24.0 mm) AL (p = 0.014). Number of leaks, rate of bilateral involvement, and recurrence rate had a negative linear association with AL (p < 0.05). Conclusion: Axial length appears to be the basic anatomical predictor, which defines morphological and clinical characteristics in acute central serous chorioretinopathy.