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March 18, 2024Alzheimer s & DementiaOpen Access

Deriving life‐course residential histories in brain bank cohorts: A feasibility study

Eleanna M. Melcher Leigha Vilen Aly Pfaff Sarah Lim Amanda DeWitt W. Ryan Powell Barbara B. Bendlin Amy Kind

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Abstract

The exposome is theorized to interact with biological mechanisms to influence risk for Alzheimer's disease but is not well-integrated into existing Alzheimer's Disease Research Center (ADRC) brain bank data collection.

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Cite This Study

Melcher et al. (2024) studied this question.

synapsesocial.com/papers/68e7388db6db6435876b1c55 https://doi.org/10.1002/alz.13773

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Practical considerations for characterization of the external exposome in Alzheimer's disease and related dementias cohortsCohort Study · 2026
2The Educational Exposome: A life‐course socioenvironmental framework for advancing Alzheimer's disease and ADRD researchreview · 2026
3Modeling approaches for estimating the effects of risk factors using longitudinal lifecourse exposure data in dementia research2025 · 2 citations
4Investigating the Role of the Exposome on Neuropathology and Biochemical Phenotypes in Alzheimer’s Disease (P7-13.008)Original Research · 2026
5Adverse Social Exposome During the Life Course and Vascular Brain Injurycohort · 2025 · 6 citations

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