The Effect of a Period of Functional Exercise with and Without Chlorella Vulgaris Supplement on some Inflammatory, Lipid Peroxidation and Antioxidant Indices in Overweight and Obese Men

Background and Objectives Obesity is related to an increase in free radicals and oxidative stress or a decrease in the antioxidant capacity of the body. The purpose of this study is investigate the effect of a period of functional exercises with and without chlorella vulgaris supplement on some inflammatory, lipid peroxidation and antioxidant indicators in overweight and obese men. Subjects and Methods This was a quasi-experimental study with a pre-test-post-test design in which 40 overweight and obese men were selected randomly and divided into 4 groups (n=10 each): placebo, supplement, placebo+exercise, and supplement+exercise. Blood sampling was done in four stages to evaluate TNF-α, hs-CRP, MDA, GPx and SOD variables. Functional exercises were performed three sessions per week continued for 12 weeks, each session lasting 60 minutes. Subjects took three 300 mg Chlorella vulgaris capsules daily. Statistical analyses were performed at a significance level of p≤0.05 using SPSS version 22. Results After adjusting the pre-test scores, the levels of serum TNF-α, hs-CRP, MDA, GPx and SOD in the post-test in the placebo, supplement, exercise and exercise+supplement groups had a statistically significant difference (p≤0.05). Comparing the groups showed that the level of serum TNF-α, CRP and MDA in the exercise group was significantly lower than that in the placebo group and that the serum level of GPx and SOD in exercise group was higher compared with the placebo group (p≤0.05). Conclusion According to the findings of the present study, it seems that chlorella supplement along with functional exercise can reduce the inflammatory and oxidative effects in obese people and increase the antioxidant effects.