Promoting Trustworthiness of Science: Reproducing and Verifying Agarwal et al.’s (2022) Findings Through Collaborative Endeavors

Ensuring the integrity and trustworthiness of science relies on reproducibility, a cornerstone of the scientific process.The availability of raw data in a FAIR manner (Findable, Accessible, Interoperable, and Reusable) is a fundamental prerequisite for this pursuit (see https://www.go-fair.org/fair-principles/).In this note, we share our experience of obtaining the raw data and successfully reproducing the results published by Agarwal et al. [1] to both provide valuable information about a specific study and to illustrate the value and challenges of reproducibility and verification investigations.We reproduced and verified the results and conclusions published in Agarwal et al.'s paper [1].The process took us almost a year, with the direct involvement of 4 investigators, led by the senior investigators and biostatisticians in our team.There were also administrative tasks involved related to the data use