Impact of antiretroviral therapy during acute or early HIV infection on virologic and immunologic outcomes: results from a multinational clinical trial | Synapse
Impact of antiretroviral therapy during acute or early HIV infection on virologic and immunologic outcomes: results from a multinational clinical trial
ART initiation during acute HIV infection improves virologic and immunologic outcomes significantly.
Findings indicate that timely treatment can enhance host immune responses and reduce the viral reservoir.
Assessment in a multinational clinical trial underscores the importance of early therapeutic interventions in HIV patients across various locations and demographics.
The results may enable earlier diagnosis and treatment of acute HIV infections to improve long-term health outcomes.
Abstract
To assess how antiretroviral therapy (ART) initiation during acute or early HIV infection (AEHI) affects the viral reservoir and host immune responses.