Inversion interferometry for superresolution of point sources in optical microscopy

Modal imaging can provide unprecedented resolution for imaging point sources, such as single-molecule fluorescent tags used to study biological samples. Among different modal imaging techniques, image inversion interferometry, where the input field is separated into symmetric and antisymmetric components, in principle allows for resolving two point sources near the quantum limit. We investigate the implementation of inversion interferometry for superresolving point sources in fluorescence microscopy. Our work focuses on the integration of this technique with microscopes used in superresolution microscopy for imaging broadband point sources and fluorophores commonly used to tag proteins in cells.