Expression of Survivin and Ki67 in Biopsy Proven Prostatic Carcinoma and Benign Prostatic Hyperplasia and its Correlation with Gleason's Score in Patients from A Tertiary Health Care Center in South Kerala

Prostatic cancer ranks the second of case fatality rate in males all over the world, second only to lung cancer [1-4]. There are over 540000 new cases diagnosed each year worldwide [5]. The classic, widely used prognostic factors for prostatic cancer are S.PSA (prostate specific antigen) serum levels, Gleason's score and staging represented by TNM system. S.PSA is widely used for prostate cancer screening and has resulted in an overall decrease in prostate cancer metastasis and death.