Biochemical analysis demonstrates binding of tryptanthrin derivative B1 to viral genome-linked protein in potato virus Y, indicating potential antiviral targeting against crop infection.
Potato virus Y (PVY) is a plant virus that is known to be responsible for substantial economic losses in agriculture. Within the PVY genome, viral genome-linked protein (VPg) plays a pivotal role in the viral translation process. In this study, VPg was used as a potential target for analyzing the antiviral activity of tryptanthrin derivatives.
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Wu et al. (2024) studied this question.
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