A point-of-care multimodal biosensor for continuous and remote monitoring of physiological signs in patients with infectious respiratory diseases

We have developed an integrated wearable to monitor skin temperature, blood and tissue oxygen saturation levels, respiratory rate, and pulse rate. The wearable was tested during different breathing exercises including breath holding, paced breathing, and hypercapnia. Preliminary data showed a consistent agreement between measurements from the wearable with signals measured from a commercial system. In addition, tissue oxygen saturation level measured at the subjects' chest corresponds better to a breathing exercise than arterial blood oxygen saturation level measured at a fingertip. This result demonstrates the capability of our wearable device in monitoring physiological signs in patients with infectious respiratory diseases.