CAR T cells refer to T lymphocytes that undergo genetic engineering to generate artificial T cell receptors, serving a crucial role in immunotherapy1. Chimeric antigen receptors (CARs) are specialized cell-surface receptors designed to identify specific proteins (antigens)2. These receptors, considered chimeric because they incorporate components from various receptors, are created by extracting T cells from the patient and modifying them in a laboratory setting3. The modified T cells then display chimeric antigen receptors, or CARs, on their surface.
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. et al. (2024) studied this question.
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