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Synapse
March 4, 20240 citationsOpen Access

Figure S8 from Intragenic Rearrangement Burden Associates with Immune Cell Infiltration and Response to Immune Checkpoint Blockade in Cancer

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HZHan ZhangHarbin Medical UniversitySLSanghoon LeeKorea Food Research InstituteRMRenee R. MuthakanaUniversity of Pittsburgh

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Abstract

Figure S8. IGR burden was not predictive of ICB benefit in a dataset for advanced melanoma treated with nivolumab (Riaz et al. Cell 2017). Treatment-naïve tumor samples showed no significant difference between responders and non-responders in terms of their IGR burden levels.

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Zhang et al. (2024) studied this question.

synapsesocial.com/papers/68e75ca9b6db6435876d4305https://doi.org/10.1158/2326-6066.25338259.v1
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