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March 2, 2024DiseasesOpen Access

Wild-Type AmpC Beta-Lactamase-Producing Enterobacterales Are a Risk Factor for Empirical Treatment Failure in Patients with Bloodstream Infection

Matteo Vassallo Roxane Fabre Laurène Lotte Sabrina Manni Christian Pradier

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Abstract

Beta-lactamases are frequently prescribed for Gram-negative bloodstream infections (BSIs). However, chromosomally encoded AmpC-producing

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Vassallo et al. (2024) studied this question.

synapsesocial.com/papers/68e76041b6db6435876d6c2c https://doi.org/10.3390/diseases12030052

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Mutation rate of AmpC-β-lactamase-producing Enterobacterales and treatment in clinical practice: A word of caution2024 · 10 citations
2Clinical Outcomes of Patients with AmpC-Beta-Lactamase-Producing Enterobacterales Bacteremia Treated with Carbapenems versus Non-Carbapenem Regimens: A Single-Center Study2024 · 4 citations
3Clinical associations and prevalence of extended-spectrum beta-lactamase and AmpC-producing Enterobacterale s: A cross-sectional studyCross-Sectional Study · 2026
4Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatmentClinical Trial · 2014 · 759 citations
5Beneficial impact of acquired AmpC β-lactamases on bacterial fitness and pathogenicity: a new paradigmOriginal Research · 2026 · 1 citations

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