429 BO50 – Ankle sprain secondary prevention: using Ankle-GO score for predicting re-injury risk two years after first occurrence. A prospective cohort study

Background Lateral ankle sprain (LAS) is the most common sport injury with a high risk of recurrence. A recently developed return to sport (RTS) score called Ankle-GO aims to assist practitioners in decision-making. However, its ability to predict the risk of re-injury remains to determine. ObjectiveS Evaluate the ability of the Ankle-GO score to distinguish LAS patients who will suffer a recurrence. Prior to data collection, we hypothesized that 2-month (M2) Ankle-GO score was able to identify patients who will suffer re-injuries. Design Prospective cohort study. Setting Baseline clinical evaluation, followed by a two-years period to determine the recurrence rate. PATIENTS 64 LAS patients were included, of whom 54 (23 males; 34.8±13.2 years) were followed to the end of the protocol. INTERVENTION Patients performed the M2 Ankle-GO and were asked whether they suffered a recurrence during the follow-up period. MAIN OUTCOME MEASURMENTS Independent t-test was used to compare the M2 score between individuals who suffered recurrence and those who did not. The Receiver Operating Characteristic (ROC) curve was used to assess the ability of the Ankle-GO score to identify the onset of LAS recurrence. Youden index (J) was used to calculate the optimal cut-off score and Odd Ratio allowed to estimate the re-injury risk. Results Two-years after the initial trauma 18 patients (33%) suffered re-injuries. Two-month Ankle-GO scores were higher among those who did not experience a new LAS (9.1±4.5 vs 5.4±2.8, p<0.01). Area under the ROC curve revealed acceptable ability of the Ankle-GO to identify recurrence (AUC=0.75; p<0.01), with an optimal cut off score of 8 points (J=0.47; sensitivity: 0.83; specificity: 0.64). Patients with a M2 Ankle-GO score <8 points were 8.8 more likely to suffer a LAS re-injury. Conclusion The Ankle-GO score at two months can predict re-injury in LAS patients and should be used in secondary prevention.