Supplementary Figure 2 from Mitochondria Transfer by Platelet-Derived Microparticles Regulates Breast Cancer Bioenergetic States and Malignant Features

Figure S2 demonstrates that the fluorescent microparticles do not simply interact bing the recipients' cell surface, but are internalized in the intracellular compartment. This is demonstrated by digestion of the cell surface receptors/ligands using pronase proteases, a common assay to distinguish between surface binding and intracellular entry.