Use of local anesthetics in individuals with chronic renal failure

Individuals with chronic renal failure (CRF) undergoing hemodialysis often develop systemic arterial hypertension (SAH) and have to consider which anesthetic should be used in dental interventions. The objective of this study was to evaluate the action of anesthetics with (AV) and without vasoconstrictor (AWV) in individuals with CRF, in need of dental treatment. Randomly, dental hemiarchs were subjected to anesthetic infiltration with a 1.8 mL tube (for one moment with AV and another moment AWV). Oxygen saturation (SaO2), heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured before and after anesthesia. The results demonstrated a statistical difference only in SaO2 5 minutes after anesthesia in comparison with the AV and AWV groups, highlighting the safety of its use, as long as in small quantities, in individuals with CRF.