Impact of Protease Inhibitors on Extracellular Crude Protease Activity Obtained From Different Strains of Aspergillus

Proteases are hydrolytic enzymes which catalyze the cleavage of peptide bond in other proteins.They have a wide range of applications particularly in food, detergent, weave, leather, pharmaceutical and chemical industries.In the present investigation protease inhibition studies were done.It gives an insight into nature of an enzyme produced by different strains of Aspergillus.Of the inhibitors tested PMSF was able to inhibit the crude protease activity obtained from all the Aspergillus strains and B-ME enhances the crude protease activity indicating that they all are thiol dependent serine proteases.