5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study

Key Points

• Participants in the intervention maintained significant weight loss, with 36% in remission from type 2 diabetes after 5 years.
• At 5 years, 81% of those who lost over 10 kg were still in remission, indicating effectiveness of the weight management strategy.
• The approach utilized continued low-intensity dietary support to sustain weight loss and enhance health outcomes over 5 years post-baseline assessment of the trial participants' progress.  A diverse group of individuals benefited, suggesting the method's broad applicability in diabetes management.

Abstract