Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

Sara Salvador‐Martín; Gianluca Rubbini; Perceval Vellosillo; Paula Zapata-Cobo; Marta Velasco Rodríguez‐Belvís; Laura Palomino; Susana Clemente; Óscar Segarra; Ana Moreno‐Álvarez; Ana Fernández-Lorenzo; Begoña Pérez‐Moneo; Montserrat Montraveta; César Sánchez; María del Mar Tolín Hernani; Inés Loverdos; María José Fobelo; Víctor Manuel Navas‐López; Lorena Magallares; Ruth García‐Romero; Ricardo Torres; Alejandro Rodríguez; Ferrán Bossacoma; Vicente Merino‐Bohórquez; Enrique Salcedo; Rebeca Álvarez; Ana Dopazo; María Sanjurjo‐Sáez; Luis A. López‐Fernández

doi:10.1016/j.biopha.2024.116299

Abstract

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Changes in gene expression profiles among individuals with inflammatory bowel diseases (IBDs) could potentially influence the responsiveness to anti-TNF treatment. The aim of this study was to identify genes that could serve as predictors of early response to anti-TNF therapies in pediatric IBD patients prior to the initiation of treatment.

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Salvador‐Martín et al. (2024) studied this question.

synapsesocial.com/papers/68e77de8b6db6435876f163f https://doi.org/10.1016/j.biopha.2024.116299

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Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

Abstract

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Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

Abstract

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