Assessment reveals an association between anti-CMV IgG seropositivity and plasma amyloid-β accumulation in middle-aged adults, highlighting infection as a potential dementia risk factor.
Some human studies have identified infection with cytomegalovirus (CMV), a member of the alpha herpesvirus family, as a risk factor for Alzheimer's disease and related dementias (ADRD). To our knowledge, no studies have evaluated associations of CMV seropositivity with plasma biomarkers of ADRD risk in middle-aged adults.
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Parker et al. (2024) studied this question.