Introduction: Giant Cell Tumor of the Bone (GCTB) around the Knee Joint poses challenges in management, particularly in the prime working-age population. This study aims to comprehensively analyze the outcomes of Extended Curettage with Cementoplasty, focusing on patient demographics, surgical interventions, joint function, local tumor control, and recurrence rates. Methodology: Our research study assessed the outcomes of Extended Curettage with Cementoplasty for GCTB around the Knee Joint in 50 patients from Januray 2020 to August 2023 in Orthopedic department of National Institute of Rehabalitation Medecine Islamabad - Pakistan. Data included demographics, tumor characteristics, surgical details, and functional scores. Joint function was evaluated using MSTS scores, while recurrence was monitored at intervals. Statistical analysis was done in SPSS. Results: A diverse age distribution (36-45 age group, 35%) and gender balance enhance the study's applicability. Extensive curettage with Polymethylmethacrylate (PMMA) augmentation (85%) correlates positively with Musculoskeletal Tumor Society (MSTS) scores. Statistical analysis reveals a significant difference (p=0.037) in MSTS scores between extensive curettage and PMMA augmentation groups. Significant improvement (28%) in joint function, especially in MSTS scores (75%), is attributed to extensive curettage and PMMA's stabilizing effects. A paired t-test shows statistical significance (p=0.005). A commendable 92% success in local tumor control substantiates the effectiveness of Extended Curettage with Cementoplasty. Chi-squared test confirms a significant difference (p=0.02) in control rates. Low recurrence rate (8%) at intervals (6, 12, 18 months) emphasizes the long-term efficacy of the intervention. Conclusion: Extended Curettage with Cementoplasty emerges as an effective strategy for GCTB around the Knee Joint, showcasing positive outcomes in joint function, local tumor control, and recurrence rates. Tailored surgical interventions play a crucial role in achieving optimal functional recovery. These findings contribute valuable insights to the evolving landscape of GCTB management.
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Alam et al. (2024) studied this question.
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