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February 19, 2024Analytical Chemistry

New Near-Infrared Fluorescence Imaging Platform with Large Stokes Shift for Carboxylesterase 2 Detection in Thyroid Cancer and Inflammatory Diseases Diagnosis

Xiaochun Wang Jian Gao Chuanfeng Fan Yingkai Gao Xintong Yang Lingxin Chen

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Abstract

Development of new near-infrared fluorophores is one of the eternal themes in the field of biosensing and biological imaging. In this work, we constructed a novel fluorophore platform MOR by replacing methylindole of hemicyanine fluorophore (CyR) with benzoxazole to acquire better fluorescence characteristics. Based on the platform, a near infrared (NIR) fluorescent probe

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Cite This Study

Wang et al. (2024) studied this question.

synapsesocial.com/papers/68e78822b6db6435876fb11f https://doi.org/10.1021/acs.analchem.3c04399

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Nonsymmetrical Near-Infrared Rhodamines for Carboxylesterase-Activatable Tumor Imaging and Photodynamic TherapyOriginal Research · 2026
2An Asymmetric NIR-II Organic Fluorophore with an Ultra-Large Stokes Shift for Imaging-Guided and Targeted Phototherapy2024 · 12 citations
3A Molecular Engineering Platform for Enhanced Stokes Shift NIR-II Fluorophores Enabling High-Fidelity 1400 nm In Vivo ImagingOriginal Research · 2026 · 1 citations
4A General Cyanine‐Based Platform for Designing Robust Dual‐Channel Near‐Infrared Fluorescent and Photoacoustic Probes2024 · 17 citations
5Molecular Engineering of Activatable NIR-II Hemicyanine Reporters for Early Diagnosis and Prognostic Assessment of Inflammatory Bowel Disease2024 · 61 citations

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