Noise gate: a physics-driven control method for deep learning denoising in x-ray imaging

Denoising algorithms are sensitive to the noise level and noise power spectrum of the input image and their ability to adapt to this. In the worst-case, image structures can be accidentally removed or even added. This holds up for analytical image filters but even more for deep learning-based denoising algorithms due to their high parameter space and their data-driven nature. We propose to use the knowledge about the noise distribution of the image at hand to limit the influence and ability of denoising algorithms to a known and plausible range. Specifically, we can use the physical knowledge of X-ray radiography by considering the Poisson noise distribution and the noise power spectrum of the detector. Through this approach, we can limit the change of the acquired signal by the denoising algorithm to the expected noise range, and therefore prevent the removal or hallucination of small relevant structures. The presented method allows to use denoising algorithms and especially deep learning-based methods in a controlled and safe fashion in medical x-ray imaging.