Objectives: In order to identify and classify the types of a secondary Parkinsonism related to intra-axial tumors, a unique case involving a 17-year-old patient diagnosed with pineoblastoma is presented. This case highlights the rare secondary Parkinsonism symptoms associated with intra-axial tumors and emphasizes the need for comprehensive assessment and early intervention in uncommon brain tumor cases. Material and methods: A comprehensive literature search was conducted using PubMed, a widely recognized and authoritative database for scientific publications. The search encompassed articles published between June, 01 and July 26, focusing on pineoblastoma-related studies. Inclusion criteria comprised papers reporting clinical cases, diagnostic criteria, and treatment modalities. Results: We found the case of an adolescent with headaches, hydrocephalus and parkinsonian symptoms due to a pineal germ cell tumor who was treated with chemotherapy and levodopa/carbidopa resulting in clinical improvement. Conclusions: Secondary Parkinsonism due to brain tumors is rare but can mimic idiopathic Parkinson's disease. Delayed diagnosis can lead to severe deficits. Timely imaging and diagnosis are crucial for management.
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Fátima et al. (2024) studied this question.
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