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Differential expression of ICI-related biomarkers and dysregulated ligand-receptor in the breast cancer study. A. Different expression of ICI-related biomarkers in responders and non-responders in each cell type. Dot plot for IFNG, IRF1, LAG3, CXCL10, CXCL11 and CXCR3. The color intensity of each dot corresponds to gene expression level, with dot’s size indicating the percentage of cells expressing that gene. B. Dysregulated IFNG-IFNGR2, CXCL10-CXCR3 and CXCL11-CXCR3 interactions in responders compared to non-responders.
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Yang et al. (2024) studied this question.
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