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Association between Helicobacter pylori Antibody and Non-Alcoholic Steatohepatitis (NASH)

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Analysis shows Helicobacter pylori correlates with liver damage in NASH patients, suggesting treatment could improve liver health.

H. pylori infection was found in 70% of NASH patients versus 40% of controls, indicating a significant association.
Patients with H. pylori exhibited elevated liver markers ALT, AST, and GGT, reflecting increased liver damage severity.
Logistic regression identified H. pylori as an independent risk factor for NASH with an odds ratio of 2.8.
Eradicating H. pylori resulted in notable improvements in liver enzymes and inflammatory markers within six months.

Obayes et al. (2025) studied this question.

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View Full Paper

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Authors

Analysis shows Helicobacter pylori correlates with liver damage in NASH patients, suggesting treatment could improve liver health.

H. pylori infection was found in 70% of NASH patients versus 40% of controls, indicating a significant association.
Patients with H. pylori exhibited elevated liver markers ALT, AST, and GGT, reflecting increased liver damage severity.
Logistic regression identified H. pylori as an independent risk factor for NASH with an odds ratio of 2.8.
Eradicating H. pylori resulted in notable improvements in liver enzymes and inflammatory markers within six months.

Obayes et al. (2025) studied this question.

View Full Paper

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