Olfactory bulbectomy v1

Q: What type of study is this?

This is a Experimental Study study.

Mario Alberto Bautista-Carro

doi:10.17504/protocols.io.81wgbwqjngpk/v1

October 7, 2025Open Access

Olfactory bulbectomy v1

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Key Points

Bilateral olfactory bulbectomy serves as a reliable model to study major depression in animal research.
The protocol details the surgical removal of olfactory bulbs, highlighting its impact on behavioral studies.
This model allows for examination of depression-related symptoms following olfactory bulb removal.
Utilizing rats in this model can improve understanding of the neurobiological aspects of depression.

Implication

Describes the protocol for olfactory bulbectomy in rats, showcasing its use in depression research.

Abstract

Bilateral olfactory bulbectomy (OBX) involves the surgical removal of both olfactory bulbs. It is a classic animal model for studying major depression. Below we describe the protocol for performing an OBX in rats.

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Cite This Study

Mario Alberto Bautista-Carro (2025) studied this question.

synapsesocial.com/papers/68e7ba40ccde5f1021f64bcc https://doi.org/10.17504/protocols.io.81wgbwqjngpk/v1

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Olfactory bulbectomy v1

Key Points

Implication

Abstract

Discussion

Cite This Study

Olfactory bulbectomy v1

Key Points

Implication

Abstract

Discussion

Cite This Study

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