Research uncovers how dynamic effects influence nucleophilic substitution outcomes at trigonal centers, suggesting alternative control mechanisms.
Singleton and co-workers have produced some wonderful work showing how dynamic effects and not just transition states can control the outcome of reactions. Steve Bachrach's blog contains many examples, including this recent one.
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Henry S. Rzepa (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: