⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

September 1, 2018Open Access

Organocatalytic cyclopropanation of an enal: (computational) assignment of absolute configurations.

View Full Paper

Ask AI

Bookmark

Share

Key Points

The study explores the organocatalytic cyclopropanation reaction involving an enal and benzyl chloride, enhancing understanding of stereochemistry.
Key findings reveal the successful assignment of absolute configurations using NMR coupling constants and computational methods.
A chiral amine acts as a catalyst, influencing the stereochemical outcomes of the reactions effectively.
This experiment provides valuable insights into mechanistic pathways, aiding undergraduate education in organic chemistry.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Implication

Laboratory experiment elucidates organocatalytic cyclopropanation and stereochemistry of enals.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Henry S. Rzepa (2018) studied this question.

synapsesocial.com/papers/68e865117ef2f04ca37e514e https://doi.org/10.59350/55cg2-hqg82

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Organocatalytic cyclopropanation of an enal: (computational) product stereochemical assignments.2018
2Organocatalytic cyclopropanation of an enal: Transition state models for stereoselection.2018
3Organocatalytic cyclopropanation of an enal: (computational) mechanistic understanding.2018
4A DFT Study on the NHC-Catalyzed Reaction of Enals with Aminoacrylates: Mechanism, Regioselectivity, and StereoselectivityOriginal Research · 2024 · 4 citations
5Theoretical Investigation on N-heterocyclic Carbene-Catalyzed Enantioselective [3 + 3] Annulation of Enal with 5-aminopyrazole for Construction of Pyrazolo[3,4-b]pyridone2024
6Mechanism and Origins of Chemo-, Regio-, and Stereoselectivities in NHC-Catalyzed Reaction of 1-Cyclopropylcarbaldehydes with α-Alkynyl Enals: A Theoretical StudyOriginal Research · 2026 · 1 citations
7Mechanistic Insight into the Origin of Stereoselectivity in NHC-Catalyzed [3 + 3] Annulation of Enal with EnamineOriginal Research · 2026 · 1 citations
8Enantioselective, Cyclopentene-Forming Annulations via NHC-Catalyzed Benzoin−Oxy-Cope ReactionsOriginal Research · 2007 · 318 citations