Systematic review assesses valve repair outcomes in patients with functional mitral regurgitation, indicating significant mortality and hospitalization rates.
A review is performed to evaluate the effectiveness of valve repair in patients with functional mitral regurgitation in terms of mortality and hospitalizations due to heart failure. Randomized clinical trials and cohort studies were included with patients who had moderate to severe mitral regurgitation, an ejection fraction of 20-50%, and NYHA functional class II-IV, despite receiving optimal medical therapy (OMT). Articles published between 2020 and 2025 in PubMed, Scopus, and Web of Science were reviewed. A total of 2,520 patients from seven studies were included. In 787 patients, the use of MitraClip was compa.
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Hernández-Montes et al. (2025) studied this question.
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