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October 11, 2025Frontiers in MedicineOpen Access

A novel biomarker Ins60/ApoA for predicting diabetic kidney disease in newly diagnosed type 2 diabetes: a pilot study

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Authors

SJSun JinMMMengqing MaHZHao Zhang

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Overview

Cross-sectional study shows Ins60/ApoA predicts diabetic kidney disease in newly diagnosed T2DM, implying potential clinical utility.

Key Points

  • Ins60/ApoA serves as an independent predictor for diabetic kidney disease in patients with T2DM.
  • With an ROC curve of 0.741, optimal ACR cutoff for predicting DKD was identified at 22.42 mg/g.
  • Higher levels of total cholesterol and fasting insulin were observed in patients with ACR ≥ 30 mg/g.
  • Negative correlations with red blood cell counts and positive correlations with blood glucose were noted in DKD patients.

Cite This Study

Jin et al. (2025) studied this question.

synapsesocial.com/papers/68e9b1c9ba7d64b6fc1327b9https://doi.org/10.3389/fmed.2025.1569730
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