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October 11, 2025Movement Disorders Clinical Practice

Response to GPi‐DBS in a Case of EIF2AK2‐Associated Early‐Onset Generalized Dystonia

Sara Radmard Kathryn Yang Darius Ebrahimi‐Fakhari

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Key Points

GPi-DBS improved dystonia symptoms in the patient, highlighting its potential effectiveness.
The intervention showed promising results, particularly in reducing severity compared to baseline status.
In this case report, GPi-DBS was successful in the management of generalized dystonia associated with EIF2AK2 mutations.
Findings may imply that GPi-DBS should be considered for similar patients with genetic forms of dystonia.

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Implication

Case report reveals GPi-DBS improved symptoms in a patient with EIF2AK2-associated dystonia, suggesting new treatment avenues.

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Cite This Study

Radmard et al. (2025) studied this question.

synapsesocial.com/papers/68ecc715d1cc7436f7d18999 https://doi.org/10.1002/mdc3.70395

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