Research note demonstrates budesonide nasal irrigation improves symptoms in allergic rhinitis, suggesting a viable alternative treatment.
International Forum of Allergy & RhinologyEarly View RESEARCH NOTE Budesonide Nasal Irrigation: An Effective Alternative Treatment for Allergic Rhinitis Navarat Kasemsuk, Navarat Kasemsuk orcid.org/0000-0001-7670-3763 Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorDichapong Kanjanawasee, Dichapong Kanjanawasee orcid.org/0000-0003-2681-2958 Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Parasitology, Biodesign Innovation Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorPremyot Ngaotepprutaram, Premyot Ngaotepprutaram Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorTriphoom Suwanwech, Triphoom Suwanwech Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorTorpong Thongngam, Torpong Thongngam Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Medicine, Division of Allergy and Clinical Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorMongkhon Sompornrattanaphan, Mongkhon Sompornrattanaphan Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Medicine, Division of Allergy and Clinical Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorChamard Wongsa, Chamard Wongsa Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Medicine, Division of Allergy and Clinical Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorTharatham Phonmanee, Tharatham Phonmanee Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorNicha Wiroonpanich, Nicha Wiroonpanich Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorSita Prakairungthong, Sita Prakairungthong Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorPattinee Juntrachu, Pattinee Juntrachu Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorKawita Atipas, Kawita Atipas orcid.org/0000-0001-6784-9525 Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorPongsakorn Tantilipikorn, Corresponding Author Pongsakorn Tantilipikorn [email protected] orcid.org/0000-0003-1995-4798 Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this author Navarat Kasemsuk, Navarat Kasemsuk orcid.org/0000-0001-7670-3763 Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorDichapong Kanjanawasee, Dichapong Kanjanawasee orcid.org/0000-0003-2681-2958 Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Parasitology, Biodesign Innovation Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorPremyot Ngaotepprutaram, Premyot Ngaotepprutaram Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorTriphoom Suwanwech, Triphoom Suwanwech Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorTorpong Thongngam, Torpong Thongngam Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Medicine, Division of Allergy and Clinical Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorMongkhon Sompornrattanaphan, Mongkhon Sompornrattanaphan Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Medicine, Division of Allergy and Clinical Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorChamard Wongsa, Chamard Wongsa Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Department of Medicine, Division of Allergy and Clinical Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorTharatham Phonmanee, Tharatham Phonmanee Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorNicha Wiroonpanich, Nicha Wiroonpanich Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorSita Prakairungthong, Sita Prakairungthong Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorPattinee Juntrachu, Pattinee Juntrachu Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorKawita Atipas, Kawita Atipas orcid.org/0000-0001-6784-9525 Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this authorPongsakorn Tantilipikorn, Corresponding Author Pongsakorn Tantilipikorn [email protected] orcid.org/0000-0003-1995-4798 Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Center of Research Excellence in Allergy and Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandSearch for more papers by this author First published: 11 October 2025 https://doi.org/10.1002/alr.70047 Trial Registration: ClinicalTrials.gov identifier: NCT06785662 Funding: This work was supported by the Faculty of Medicine Siriraj Hospital, Mahidol University (no. (IO) R016533024). Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechatBluesky No abstract is available for this article. References 1K. Lam, B. K. Tan, J. M. Lavin, E. Meen, and D. B. Conley, "Comparison of Nasal Sprays and Irrigations in the Delivery of Topical Agents to the Olfactory Mucosa," Laryngoscope 123, no. 12 (2013): 2950–2957, https://doi.org/10.1002/lary.24239. 10.1002/lary.24239 PubMed Web of Science® Google Scholar 2K. Snidvongs, E. Pratt, D. Chin, R. Sacks, P. Earls, and R. J. 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Togias, et al., "Next-Generation Allergic Rhinitis and Its Impact on Asthma (ARIA) Guidelines for Allergic Rhinitis Based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and Real-World Evidence," Journal of Allergy and Clinical Immunology 145, no. 1 (2020): 70–80, https://doi.org/10.1016/j.jaci.2019.06.049. 10.1016/j.jaci.2019.06.049 PubMed Web of Science® Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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