Evaluation of the relationship between quorum sensing system genes and antibiotic resistance in isolated Pseudomonas aeruginosa from cystic fibrosis patients
Analysis reveals significant antibiotic resistance in Pseudomonas aeruginosa isolated from cystic fibrosis patients, indicating a strong link to quorum sensing genes.
Key Points
Over 61% of Pseudomonas aeruginosa strains exhibited multiple-drug resistance, indicating a serious health concern.
The most common quorum sensing gene in resistant strains was rhlR, highlighting its potential role in antibiotic resistance mechanisms.
Antibiotic resistance was assessed using the disk diffusion method, providing reliable insights into the resistance patterns of the isolates.
The findings suggest that addressing quorum sensing could be vital in developing effective treatments against resistant Pseudomonas aeruginosa.