Sign-Problem-Free Nuclear Quantum Monte Carlo

Quantum Monte Carlo (QMC) methods offer exact solutions for quantum many-body systems but face severe limitations in fermionic systems like atomic nuclei due to the sign problem.While sign-problem-free QMC algorithms exist, they have been confined to simple models with limited predictive power for real nuclei.Here we overcome this barrier by developing a novel lattice nuclear force that is rigorously sign-problem-free for even-even nuclei. This interaction achieves a standard deviation of $σ= 2.932$ MeV from experimental binding energies for 76 even-even nuclei (N,Z ≤ 28), matching state-of-the-art phenomenological mean-field models.Key innovations include the first sign-problem-free implementation of spin-orbit coupling for shell evolutions and an efficient QMC-optimized framework for global parameter fitting.Using this approach, we compute binding energies from ⁴He to ¹³²Sn, symmetric nuclear matter saturation, and reveal novel spin-orbit-driven clustering in light nuclei. This work transforms sign-problem-free QMC into a scalable and predictive nuclear structure tool, establishing a non-perturbative foundation for ab initio calculations extending to heavy nuclei.