This review shows how virtual fetal holography enhances understanding of fetal development, highlighting its potential in prenatal counseling.
Introduction Effective prenatal counseling relies on clear communication of fetal development and potential complications. Conventional 2D and 3D ultrasound images often fail to intuitively convey complex anatomy to expectant parents, limiting engagement and informed decision-making. Content Virtual fetal holography combines advanced image processing and 3D/4D ultrasound data to generate interactive, life-like fetal models. This review synthesizes current literature on its technological basis, clinical applications, and patient-centered outcomes. Evidence from cardiology, surgical planning, and anatomy education demonstrates how holography improves spatial understanding, supports multidisciplinary counseling, and enhances patient experience compared to standard imaging. Applications in anomaly counseling, maternal–fetal bonding, and clinical training are highlighted, alongside workflow models integrating mixed reality headsets and AI algorithms. Summary Virtual fetal holography shows potential for improving prenatal education and emotional engagement. Current evidence is largely descriptive and feasibility-based, with limited empirical validation of its impact on clinical decision-making or patient outcomes. Outlook Future research should address cost, technical complexity, ethical considerations, and standardized clinical protocols. Large-scale trials and cost-effectiveness analyses are needed to define its role in routine prenatal care.
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Andonotopo et al. (2025) studied this question.
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