A Study on Spectrum of Disease and Clinicohistopathological Correlation in Hansen's Patients Attending Dermatology Opd in a Tertiary Care Hospital

Background And Objectives : The present study was undertaken to study the clinical prole of patients and their histopathological correlation with clinical presentation. Materials And Methods: Prospective Longitudinal study from January 2019 to June 2021 at Department of Dermatology Venereology and Leprosy,Chengalpattu Medical College& Hospital,Chengalpattu of 100 patients.Detailed history taken and classied clinically on the basis of Ridley Jopling and WHO classication.Slit skin smear and biopsy performed in all cases at the time of diagnosis and clinicohistopathological correlation made. Results: The higher number of patients belongs to Borderline Tuberculoid Hansen's disease because these patients come early for treatment because of its neurological symptoms and reactions.SSS-AFB positivity is found in 44% of patients and gives indication about the level of contagion in the community.Histologically, the common classication made was Borderline tuberculoid.Clinico-histopathological correlation is seen in 84.48% of the patients. Maximum correlation was observed in Lepromatous leprosy. Interpretation And Conclusion: The correlation of clinical and histopathological features along with bacteriological index is more useful for accurate typing of leprosy than considering a single parameter alone. Clinical improvement of skin lesions and the mean fall of bacteriological index can be used for followup of patients.