Effect of Enzyme Supplemented Cassava Peel – Maize Cob Mixture on Histopathological Examination of Liver of Growing Pigs

This study assessed the effect of enzyme supplemented cassava peel – maize cob mixture (CPM-CM) on histopathological examination of growing pigs. Gilts were assigned randomly to four treatments (n = 10 pigs/ treatment). Each treatment consists of 5 replicate with 2 pigs each in a completely randomized design. Enzyme supplemented dried cassava peel and maize cob meal (CPMCM) at ratio 1:1 was incorporated into the experimental diet to replace maize as follows: treatment 1 (T1) control diet (0 % CPMCM with enzymes), T2 (10 % CPM-CM with enzymes), T3 (20 % CPMCM with enzymes), T4 (30 % CPMCM with enzymes). The trial lasted for 60 days, feed and water was given ad libitum. Evaluation of phyto-constituents in CPM-CM revealed the presence of Saponins (208.2 mg/100g), flavonoids (123.4 mg/100g), tannins (51.82 mg/100g), alkaloids (109.8 mg/100g), phenols (87.12 mg/100g) and cyanide (3.45 mg/100g). Outcome on hepatic histopathology shows normal tissue architecture with normal central vein, hepatic lobules, hepatic sinusoids, portal tract and biliary tract. There was absence of congestion in the portal blood vessels and coagulative necrosis. It was concluded that feeding different levels of CPM-CM up to 30 % had no toxic effect on liver tissues and was able to neutralize the activities of free radicals in the cells of animals