The Potential Mechanisms and Therapeutic Approaches of Gut Microbiota and the Occurrence of Endometritis

Endometritis, a prevalent gynecological condition, remains incompletely understood in terms of its pathogenesis, with inflammatory responses being a key factor in its development. In recent years, a growing body of research has highlighted that gut microbiota imbalances may significantly impact the onset and progression of endometritis. Currently, antibiotics are the mainstay of clinical treatment for endometritis, but the emergence of drug resistance problems has brought many challenges to the treatment. Due to the incomplete clarification of the pathogenesis of endometritis, there is a lack of more targeted treatment strategies and methods. This study thoroughly examined the potential mechanisms linking gut microbiota to endometritis occurrence, and explored the corresponding treatment methods, initially screening out four possible action pathways and two potentially feasible treatment options, providing a theoretical basis and reference direction for subsequent related studies. However, these conclusions still need to be further verified through experimental studies. Future research should focus on conducting experimental work to deeply explore its mechanism and optimize the treatment strategy.