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October 16, 2025Journal Syifa Sciences and Clinical ResearchOpen Access

Clinical Outcomes of Antihypertensive Therapy in Chronic Kidney Disease: A Literature Review

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Authors

ICI Dewa Agung Ayu Diva CandraningratDHDewa Ayu Sri HandaniNPNi Putu Vyra Ginanti Putri

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Overview

Literature review shows antihypertensive therapy improves cardiovascular outcomes in CKD, suggesting RASi as first-line treatment.

Key Points

  • Renin-angiotensin system inhibitors significantly lower blood pressure and reduce eGFR decline in CKD patients.
  • Azilsartan demonstrated greater effectiveness in reducing urine protein and controlling blood pressure compared to candesartan.
  • Calcium channel blockers like benidipine are beneficial for renal outcomes over amlodipine, indicating class-specific effects.
  • The individualization of antihypertensive treatment in CKD is crucial based on patient-specific factors and follow-up.

Cite This Study

Candraningrat et al. (2025) studied this question.

synapsesocial.com/papers/68f04935e559138a1a06e27fhttps://doi.org/10.37311/jsscr.v7i3.34331
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