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October 16, 2025Molecular BiomedicineOpen Access

Single-cell multi-omics in biliary tract cancers: decoding heterogeneity, microenvironment, and treatment strategies

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Authors

NTNannan TangJLJiatong LiAGAo Gu

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Overview

Review reveals tumor heterogeneity and microenvironment in biliary tract cancer, suggesting novel treatment strategies.

Key Points

  • Single-cell multi-omics elucidates tumor heterogeneity in biliary tract cancer, revealing complexities in tumor biology.
  • Analysis integrates genomics, transcriptomics, and epigenomics to construct a molecular atlas, enhancing understanding of biliary tumors.
  • These technologies highlight tumor microenvironment remodeling and immune cell populations, pointing to potential novel therapeutic interventions.
  • Personalized treatment strategies informed by insights from single-cell technologies may foster innovations in biliary tract cancer management.

Cite This Study

Tang et al. (2025) studied this question.

synapsesocial.com/papers/68f0d5eb105731330a2b1ebfhttps://doi.org/10.1186/s43556-025-00330-2
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