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October 16, 2025Journal of Clinical MedicineOpen Access

Liver Enzyme Elevations in Rheumatoid Arthritis: Clinical Relevance and Influence on Treatment Strategies

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Authors

YAYahya AtayanSYServet YolbaşEBEmin Bodakçi

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Overview

Retrospective evaluation shows liver enzyme changes in RA patients affect treatment strategies, suggesting importance of monitoring.

Key Points

  • Elevated liver enzymes in RA can impact treatment strategies and necessitate dose adjustments.
  • Of the 33 RA patients evaluated, 18 developed liver enzyme abnormalities during treatment, affecting therapy choices.
  • 21% of patients on methotrexate maintained elevated liver enzymes, leading to treatment modifications in some cases.
  • Hepatotoxicity risk in RA patients can be managed with careful monitoring, with dose reductions being effective.

Cite This Study

Atayan et al. (2025) studied this question.

synapsesocial.com/papers/68f17f111f11f0e857c5347fhttps://doi.org/10.3390/jcm14207213
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