Engineering alkyl spacers allows for simultaneous modulation of chirality and mechanical properties in supramolecular hydrogels, suggesting new applications in synthetic biology.
Mimicking the extracellular matrix’s (ECM) integration of chiral and mechanical cues remains challenging in synthetic hydrogels. Here, we demonstrate alkyl spacer engineering in C2-symmetric benzene-para-dicarboxamide phenylalanine derivatives enables simultaneous control...
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Zhang et al. (2025) studied this question.
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